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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA2
All Species:
32.42
Human Site:
Y426
Identified Species:
71.33
UniProt:
Q15349
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15349
NP_001006933.1
733
83239
Y426
E
D
I
G
V
G
S
Y
S
V
C
K
R
C
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001107921
680
76674
S385
T
A
R
T
P
T
D
S
P
G
V
P
P
S
A
Dog
Lupus familis
XP_855268
754
85566
Y447
E
D
I
G
V
G
S
Y
S
V
C
K
R
C
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUT3
733
83138
Y426
E
D
I
G
V
G
S
Y
S
V
C
K
R
C
V
Rat
Rattus norvegicus
Q63531
735
82865
Y429
E
T
I
G
V
G
S
Y
S
V
C
K
R
C
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513942
700
79225
Y393
E
D
I
G
V
G
S
Y
S
I
C
K
R
C
I
Chicken
Gallus gallus
P18652
752
84421
Y446
E
A
I
G
V
G
S
Y
S
V
C
K
R
C
I
Frog
Xenopus laevis
P10665
733
82620
Y427
E
T
I
G
V
G
S
Y
S
V
C
K
R
C
V
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
Y431
E
D
I
G
V
G
S
Y
S
I
C
K
R
C
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
Y634
T
R
T
S
N
G
A
Y
G
T
C
H
F
V
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21734
784
88102
H465
E
K
I
G
N
G
A
H
S
V
V
H
K
C
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
84.7
93.9
N.A.
95.6
77.1
N.A.
80.3
76.4
75
75.8
N.A.
23.9
N.A.
56.7
N.A.
Protein Similarity:
100
N.A.
86.2
95.2
N.A.
97.8
87.6
N.A.
87.8
86.4
84.9
85.9
N.A.
37.7
N.A.
71.5
N.A.
P-Site Identity:
100
N.A.
0
100
N.A.
100
93.3
N.A.
86.6
86.6
93.3
86.6
N.A.
26.6
N.A.
46.6
N.A.
P-Site Similarity:
100
N.A.
0
100
N.A.
100
93.3
N.A.
100
93.3
93.3
100
N.A.
33.3
N.A.
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
0
0
0
19
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
82
0
0
82
0
% C
% Asp:
0
46
0
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
82
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
82
0
91
0
0
10
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
19
0
0
0
% H
% Ile:
0
0
82
0
0
0
0
0
0
19
0
0
0
0
28
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
0
73
10
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
10
0
0
10
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
10
10
0
0
0
0
0
0
0
0
0
73
0
0
% R
% Ser:
0
0
0
10
0
0
73
10
82
0
0
0
0
10
0
% S
% Thr:
19
19
10
10
0
10
0
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
73
0
0
0
0
64
19
0
0
10
55
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _